
🌟 Who Is a Good Candidate?
You may benefit if you have:
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Dark circles
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Under‑eye hollows
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Crepey or thin skin
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Early under‑eye bags
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Puffiness from inflammation
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Filler complications or “pillow face”
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A desire for natural, subtle rejuvenation
This treatment is ideal for patients who want regeneration, not volume‑stuffing.

🧊 What Is Wharton’s Jelly MSC Under‑Eye Treatment?
Wharton’s Jelly MSCs are derived from the umbilical cord matrix and contain:
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Mesenchymal stem cells
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Growth factors
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Cytokines
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Structural proteins
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Billions of exosomes
These biologic components help:
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Strengthen thin under‑eye tissue
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Stimulate collagen and elastin
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Improve support and volume naturally
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Reduce inflammation and puffiness
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Enhance firmness and skin quality over time
The result is a smoother, brighter, more supported under‑eye contour without the risks of filler migration or lumpyness


🌿 Why Patients Choose Our Under‑Eye Rejuvenation
✨ Natural, Not Overfilled
We avoid the risks of under‑eye filler and instead use regenerative approaches that improve your own collagen, elasticity, and tissue quality.
🧬 Regenerative Medicine Expertise
Wharton’s Jelly MSCs contain growth factors, cytokines, and extracellular matrix components that support healthier, firmer under‑eye skin.
👁️ Safe for All Skin Types
Our approach is ideal for patients with thin skin, pigmentation, or filler complications.
🩺 MD‑Led Care
All treatments are performed or supervised by Dr. Kathryn Schaefer, MD — Board‑Certified and trusted in Honolulu for over 25 years.
🔬 Our Under‑Eye Treatment Options
🧬 Wharton’s Jelly Stem Cellls
Regeneration Supports collagen, improves firmness, and reduces inflammation.
📡 RF Microneedling (Gentle Under‑Eye Protocol)
Tightens crepey skin and stimulates collagen.
💡 Pico Laser Brightening
Improves pigmentation and dark circles safely for all skin tones.
❄️ CO₂ Laser (Light Under‑Eye Resurfacing)
Smooths fine lines, tightens skin, and improves texture.
💧Tear Trough Filler
Hyaluronic acid filler can soften under‑eye hollows and reduce shadowing for a brighter, more refreshed appearance.
We customize every plan based on your anatomy, skin type, and goals.

🧭 What to Expect
⏱️ Treatment Time: 20–30 minutes
💤 Comfort: Topical numbing available
⏳ Downtime: Minimal
🌱 Results: Gradual improvement over 4–12 weeks
🔁 Recommended: 1–3 sessions depending on severity
Regenerative treatments build results over time as your tissue strengthens and inflammation decreases.

🛡️ Why Patients Prefer Regeneration Over Fillers Under the Eyes
💧 No Tyndall effect (blue tint)
🚫 No filler migration
🌿 No “puffy under‑eye” look
🧬 Improves your own tissue instead of masking the problem
👁️ Safer for thin, delicate under‑eye skin
This is why physician‑led clinics increasingly choose regenerative medicine instead of tear‑trough fillers.

📸 Before & After Expectations
Results vary based on:
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Skin thickness
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Degree of hollowness
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Pigmentation
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Inflammation
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Lifestyle factors
Most patients see:
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Brighter under‑eyes
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Smoother texture
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Less crepiness
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Reduced puffiness
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More support and firmness
We can also combine treatments for enhanced results.

Frequently Asked Questions
❓ How does under‑eye Wharton’s Jelly MSC treatment work? Wharton’s Jelly MSCs contain growth factors, cytokines, and extracellular matrix components that support collagen, improve elasticity, and reduce inflammation. Over time, this strengthens thin under‑eye tissue and improves brightness and firmness.
❓ Is this treatment safe for the under‑eye area? Yes. The biologic components used are well‑tolerated, and the under‑eye protocol is performed by or under the supervision of a Board‑Certified MD. While cosmetic under‑eye MSC studies are limited, regenerative medicine research supports their safety and tissue‑repair properties.
❓ How is this different from under‑eye filler? Fillers add volume but can migrate, cause puffiness, or create a blue tint (Tyndall effect). Wharton’s Jelly MSCs do not “fill” — they regenerate your own tissue, improving support and quality without the risks of overfilling.
❓ How many treatments will I need? Most patients benefit from 1–3 sessions depending on skin thickness, hollowness, and pigmentation. Regenerative treatments build gradually, so improvements continue over several months.
❓ When will I see results? You may notice early brightness within a few weeks, with collagen‑driven improvements appearing between 4–12 weeks. Results continue to evolve as the tissue strengthens.
❓ Is there downtime? Downtime is minimal. You may experience mild swelling or redness for 24–48 hours.
Most patients return to normal activities the same day.
❓ Can this help with dark circles? Yes — especially when dark circles are caused by thin skin, inflammation, or poor microcirculation. For pigment‑based dark circles, we may combine MSC therapy with Pico laser brightening for optimal results.
❓ Can this help with under‑eye bags? Mild puffiness caused by inflammation may improve. Structural fat‑pad herniation (true “bags”) may require a different approach. Your consultation will determine the best plan.
❓ Is this safe for all skin types, including Asian skin? Absolutely. Regenerative treatments are ideal for melanin‑rich skin because they do not use heat or aggressive lasers. This makes them a preferred option for Asian and Pacific Islander patients.
❓ How long do results last? Results vary, but many patients enjoy long‑lasting improvement due to the regenerative nature of the treatment. Maintenance sessions can be done yearly if desired.
❓ Can I combine this with other treatments? Yes — and combination therapy often gives the best results. Popular pairings include: • RF microneedling for crepey skin • Pico laser for pigmentation • PRP for additional brightening • CO₂ laser for fine lines • EM Slim Neo for facial contouring support
❓Who performs the treatment? All procedures are performed or supervised by Dr. Kathryn Schaefer, MD — Board‑Certified with over 25 years of medical experience.


🧊 About WJ MSC
Our Wharton’s Jelly–derived matrix containing:
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Mesenchymal stem cells
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Growth factors
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Cytokines
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Structural proteins like collagen
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Billions of exosomes
It is stored and shipped frozen to preserve potency and ensure maximum regenerative benefit at the time of treatment. Tested by 2nd party labs for pathogens and sterility
🌿 Related Regenerative Treatments
Explore other physician‑led regenerative options available at our Honolulu clinic:
💎 Baby Face™ Stem Cell Facial For collagen renewal, smoother texture, and youthful radiance.
💠 Hair Restoration (MSC + PRP) For thinning hair, shedding, and early hair loss. Supports follicle health and natural regrowth.
💪 Shoulder Pain / Rotator Cuff Treatment For tendon injuries, overuse pain, and rotator cuff degeneration. Helps reduce inflammation and support tissue repair.
Book your under eye Under‑Eye Rejuvenation
Ready to look more rested and get rid of those bags?

